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Additionally, melatonin reduced the activities of other kinases involved in tau hyperphosphorylation, such as CDK5, through the upregulation of micro-RNAs [115]

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There has many researches about increasing the production of l-cysteine, such as reduced the degradation of l-cysteine by disrupting the l-cysteine degradation genes [19] or overexpressed the l-cysteine synthetases to increase the l-cysteine concentration [20, 21]