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This process leads to the release of chromatin through a ruptured nuclear envelope, where it combines with cytosolic antimicrobial proteins and extracellular DNA (116, 120)

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Common pitfalls with cell viability assays are: Assays lack sensitivity threshold required for reproducibility and high-throughput screening Lacking an option for kinetic monitoring Viability assays measure how many cells are alive, but not whether theyre actively dividing