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Reducing disc bulging is often achieved through decompression or discectomy (mechanical, thermal, or chemical), in which a portion of IVD is removed to decompress the spinal canal and destroy the blood and nociceptive fibres that could have formed in the periphery of the disc during degeneration [108]

While these trials are limited in size and scope, they provide a stronger translational basis for certain research applications compared to BPC-157s exclusively preclinical evidence base

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