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Besides regulating T cell proliferation, glutamate availability is also indicated to influence the T H 2 and T H 1 cytokine production by T cells

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Discussion The results of this study show that either the acute- or short-term administration of the peripheral DBH inhibitor, etamicastat, decreases blood pressure in both non-anesthetized and anesthetized mice with germ line deletion of Drd2 or renal-selective silencing of Drd2 (renal subcapsular infusion of Drd2 siRNA in D 2 +/+ mice) but not in wild-type littermates or D 2 +/+ mice that received renal subcapsular infusion of non-silencing siRNA

10.1016/j.fct.2018.08.024 67 UpadhyayS.RahmanM.JohansonG.PalmbergI.GangulyK