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and bioorthogonal conjugation of immunomodulators to the EcN surface, where dissolution of an enteric coating in the intestine exposes the conjugates to drive macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2, complementing the probiotic's intrinsic effects (Peng et al., 2024)

Patients with heart rhythm disorders or those taking medications that affect heart rhythm should discuss hydroxyzine use with their healthcare provider before starting treatment

Tirzepatide side effects Common Side Effects The most common tirzepatide side effects are: Diarrhea Vomiting Constipation Nausea (mild to moderate) Decreased appetite Abdominal pain