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Tumorigenesis-associated metabolic reprogramming affects the genomic status by regulating the enzymes for epigenetic modifications, which commonly utilize key metabolites as either substrates or allosteric regulators (Etchegaray and Mostoslavsky, 2016
doi: 10.1042/BCJ20210263 184 LumkwanaD.PeddieC.KrielJ.MichieL
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