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97 , E907E916 (2012)

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This downregulation is followed by a decrease in nonmethylated cytosine levels and an increase in DNMT1 and DNMT3A methyltransferases

GLP1/E, at very low doses, is sufficient to ameliorate PCOS-associated metabolic alterations Since GLP1/E was superior to any other compound in terms of improvement of metabolic traits, we next assessed the metabolic efficacy of very low doses of this multi-agonist in our metabolically dysregulated PCOS model