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During a meal, this effect reduces the intestinal delivery of gastric contents resulting in a smaller glucose excursion, one of the mechanisms of action for diabetes therapeutic drugs 14

Courty MH, Hao Q, Krishnaswamy S, Bekaii-Saab T, Al-Rohaimi A, VonMoltke LL, Greenblatt DJ: UDP-glucoronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucoronidation by human liver

However, mTORC1 activation only promoted metabolic reprogramming of Gclc -deficient FoB but was not sufficient to ensure antibody production, in contrast to B cell cells isolated from tuberous sclerosis complex 1 (TSC1)-deficient mice 102