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Among the various forms of cell death, ferroptosis has recently emerged as a unique, iron-dependent modality of programmed cell death that has gained significant scientific interest (2)

[DOI] [PubMed] [Google Scholar] Obach RS and Dalvie DK (2006) Metabolism of nomifensine to a dihydroisoquinolinium ion metabolite by human myeloperoxidase, hemoglobin, monoamine oxidase A, and cytochrome P450 enzymes

They mostly target the MC1R (melanocortin 1 receptor) found on the surface of skin cells called melanocytes