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Feb 28 2020;26(2):247-263

In a rigorous review of 19 randomized controlled trials that enrolled type 2 diabetics, acarbose was found to significantly reduce HbA1C levels when given alone or as add-on treatment with other antidiabetic drugs (Derosa 2012)

Gliadin has been reported to trigger T1D development in non-obese diabetic mice and Bio Breeding Diabetes Prone rat models

For this reason, several novel NBDHEX analogues, with improved selectivity for GSTP1-1, have been synthesized and characterized to obtain new therapeutic opportunities for the treatment of drug resistant tumors including human melanoma 100,101