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Immunity 56 , 20362053.e12 (2023)

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Mounting evidence, including the recent (and unprecedented) phase 2 data on retatrutide, supports a role for incretin hormone agonists in treating obesity

Users maintaining excellent sun protection, adequate moisturization, healthy diet supporting collagen synthesis (adequate protein, vitamin C, copper from foods), sufficient sleep, stress management, and avoidance of collagen-damaging habits (smoking, excessive alcohol) preserve treatment gains better than users with suboptimal skincare and lifestyle creating ongoing skin stress overwhelming GHK-Cu induced improvements