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Retatrutide establishes the foundation and should be started first, with dose escalation occurring over 8-12 weeks

But Dr Simon Cork, a senior lecturer in physiology at Anglia Ruskin University in Cambridge, told MailOnline: 'This is essentially a sign that the drugs are working at reducing weight.' He said: 'The buttocks are one of the areas of the body where we deposit excess fat, more so in some people than others