Rare side effects of B12 shots (require medical attention) Serious reactions to B-12 shots are uncommon, but its important to be aware of them: Allergic reaction, including rash, hives, dizziness, or trouble breathing Significant swelling, pain, or warmth that worsens at the injection site Palpitations or chest discomfort Signs of drug interactions, especially if you take multiple prescription medications If you experience symptoms that feel intense, progressive, or unusual, you should contact your provider right away
It is difficult to self-inject in this spot, so usually a trained spouse, friend or healthcare professional is needed for a shot of B12 in your arm
No heating should be required at typical use concentrations
High-intensity cardio is less important during this combination