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Figure S2 The cell integrity is preserved under the conditions of staurosporine (STS) treatment that lead to glutathione export

Besides preventing the induction of the sarcopenia-related markers HDAC4, MyoD, myogenin, and rescuing the downregulation of PGC1, the co-administration of both ingredients attenuated the reduction of MyHC isoforms, downregulated the expression of Atrogin-1 and MuRF1, prevented age-induced macrophage infiltration, and activated the insulin-dependent PI3K/Akt pathway in gastrocnemius muscle and adipose tissue [297]

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction