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The researchers noted that after weight loss, T3 decreased significantly, and a decrease in peripheral conversion of the prohormone T4 into its hormonally active metabolite T3 is at least in part responsible for the observed changes in thyroid hormone homeostasis. What weight goal should you have to control hypothyroidism

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It is not yet approved and is still working through larger studies, so it is one to watch rather than something available today, but it shows just how far this class of medicines has pulled ahead of anything a supplement can offer