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In the SURMOUNT-1 trial, tirzepatide produced average body-weight losses of 15.0% at 5 mg, 19.5% at 10 mg, and 22.5% at 15 mg over 72 weeks, compared with 3.1% for placebo (Jastreboff et al., NEJM 2022)

It is worth mentioning that Novo Nordisk also submitted a Priority Review Voucher (PRV) to speed up the NDA review, which can shorten the NDA review cycle from the standard 10 months to 6 months

Metabolomic markers of antepartum depression and suicidal ideation

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