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Starting with a low dose, maintaining hydration, and eating small meals can reduce mechanical stress on your colon while taking semaglutide

SCHAFER, E.W

10.1158/1055-9965.epi-20-0833 37 EstivalA.SanzC.RamirezJ

In another study treatment with 20nM Ex-4 on rat adipose-derived MSC additionally elevated OPG and RUNX2 protein levels, while reducing osteoclast activity [29]