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Conclusion Despite the limitations of SH-SY5Y cells as an in vitro model, our results suggest that guarana and caffeine, alone or in combination with taurine, may exert neurotoxicological effects in part by disruption of redox homeostasis (Figure 14), which is also consistent with the data obtained in the in silico approach (Figure 13)

To view a copy of this licence, visit About this article Cite this article Vakrinou, A., Murphy, E., Sisodiya, S.M

Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo