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Common gastrointestinal effects reported with GLP-1 therapy include: Nausea (commonly reported, especially during dose escalation) Constipation or diarrhoea Abdominal discomfort or bloating Reduced appetite and early satiety Regarding bowel movement colour specifically, changes in stool colour are not listed as adverse effects in UK SmPCs for GLP-1 receptor agonists

Licensed providers can reassess and adjust the treatment plan - including medication or dosage - when the initial approach is not producing the intended results, when clinically appropriate

The skins outermost layer, the stratum corneum, effectively blocks most molecules from being absorbed

Published 2025 Mar 4