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Easy to Use: Simply apply over clean, dry blemish and leave on for several hours (or overnight) for optimal effects

Kang HJ, Chen N, Dash BC, Hsia HC, Berthiaume F

S100A8, S100A/8 and S100A9 proteins were purchased from R&D Systems (#9876-S8-050, #8226-S8-050 and #9254-S9-050, respectively)

Gal3 is able to sense damaged lysosomes, where they accumulate to induce further lysophagy by recruiting autophagy regulatory factors, including uncoordinated-51-like kinase 1 (ULK1), Beclin 1, and autophagy-related protein 16L1 (ATG16L1) after binding with E3 ubiquitin ligase-tripartite domain containing protein 16 (TRIM16) 86