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Clinical approach considerations: Patient selection: Stable post-surgical patients with inadequate weight loss, weight regain, or persistent metabolic disease Timing: Individualized based on weight trajectory and metabolic status, often when weight loss plateaus or regain is documented Baseline evaluation: Comprehensive metabolic panel, nutritional markers (vitamin B12, iron studies, vitamin D, calcium, albumin), HbA1c if diabetic, lipid panel, assessment of gastrointestinal symptoms, renal function Dosing strategy: For Wegovy, initiate at 0.25 mg weekly with gradual titration (0.250.51.01.72.4 mg)

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Primes GLP-1 Pipeline Update provides a credible clinical snapshot of what is on the horizon

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