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Description

Activated PKA and EPAC2 can close ATP-dependent K + channels and voltage-dependent K + channels, leading to membrane depolarization and the activation of voltage-dependent calcium channels (VDCC), resulting in Ca 2+ influx

NMB, neuromedin B

Graphical abstract was created by BioRender ( Funding Statement The author(s) declare that no financial support was received for the research, and/or publication of this article