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52 thus began the competition between various GLP-1RAs

But registration alone tells you very little

Variables are presented as percentages or means with standard deviations

DHODH activity is essential for proliferating cells owing to their increased demand for nucleotides, and DHODH inhibition has long been studied as a therapeutic strategy in autoimmune diseases (for example, via leflunomide) and cancer, where it can lead to cell cycle arrest, DNA damage and replication stress 42,44,45