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Digestive enzymes present in the saliva may also irritate the lips, and the evaporation of the water in saliva saps moisture from them

Methylation pathways become saturated, and excess methionine is converted to homocysteine, which may contribute to cardiovascular risk if B-vitamin cofactors (B6, B12, folate) aren't adequate

Combination antioxidants Compounds commonly used to alleviate oxidative stress exhibit different antioxidant actions, and so there exists the potential for different antioxidants to work together to improve whole cell and organ function through a targeted polypharmaceutical approach to decrease oxidative stress

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