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The approval was supported by liver biopsybased histological assessments from the first 800 patients after 72 weeks of treatment: Primary Endpoint 1: Resolution of steatohepatitis with no worsening of liver fibrosis Semaglutide group: 62.9% achieved the endpoint Placebo group: 34.3% achieved the endpoint Primary Endpoint 2: Improvement in liver fibrosis with no worsening of steatohepatitis Semaglutide group: 36.8% achieved the endpoint Placebo group: 22.4% achieved the endpoint Figure 1

A further clinical trial called SELECT found that Wegovy produced clinically significant weight loss after 208 weeks

Sneha Dave, executive director of Generation Patient, an advocacy group for young adult patients, said federal regulations that govern drug promotion havent kept up with changes in social media such as the growth of short-form video on Instagram and TikTok

France isnt the only country taking a cautious approach to the medicines