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Identifying joint hypermobility syndromes and measuring the impact Joint hypermobility, characterised by an excessive range of motion in the joints, poses unique challenges for both patients and healthcare providers when symptoms arise

In practice, clinicians may consider it for weight management support in adults with overweight or obesity, particularly when lifestyle measures alone have not been sufficient

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Clinical approach recommendations include starting with the most conservative effective therapy, optimizing tirzepatide dosing before adding other agents, regular monitoring of cardiovascular parameters and metabolic markers, and setting realistic weight loss goals (5-10% initial target)