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Figure 2 4.3 Analysis of outcomes following control group and study group: utilizing the previous IVF cycle as a self-control To assess the impact of L-carnitine, we compared outcomes from cycles following its administration with those from prior cycles, which served as the self-control group

The researchers suggested the benefits of GLP-1s before pregnancy could be negated or attenuated by the adverse effects of GLP-1 discontinuation. They added the higher risk for gestational weight gain may contribute to the increased risk for hypertensive disorders of pregnancy and gestational diabetes given the established relationship between gestational weight gain and adverse pregnancy outcomes. Maya told Healio that many individuals are on GLP-1s before pregnancy and are benefiting tremendously. Clinicians following these patients need to know that when their patients stop these medications for pregnancy, they are at risk for greater gestational weight gain and greater risk for gestational diabetes, hypertensive disorders of pregnancy and preterm delivery, she said

This is why GLP-1 treatments must always be prescribed and monitored by a healthcare professional