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While there may be overlap with presentations of long COVID in adults, appropriate management of long COVID in children, including MIS-C, requires consideration of pathophysiology, biology, pharmacology, neurocognitive and behavioral development unique to children (155), which is beyond the scope of this article

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Infected macrophages display reduced mitochondrial membrane potential and decreased ATP levels, leading to impaired antimicrobial effector functions ( 5.3 Parasite-induced oxidative stress and mitochondrial dysfunction Parasite-induced oxidative stress plays a dual role in infection dynamics