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Moreover, in those patients with neurologic signs an electroencephalography (EEG) recording should also be performed to rule out PS, a benign epileptic syndrome, characterized by predominantly autonomic symptoms (including emesis): the availability of EEG recording in pediatric ED might be useful for a prompt and not-cost-consuming diagnosis (133)

The blood-ocular barrier (BOB) includes the blood-aqueous barrier (BAB) located in the anterior segment of the eye and the blood-retinal barrier (BRB) located in the posterior segment of the eye, which can restrict the entry of drugs from the blood into the eye and is the main obstacle in treating eye diseases (Lyu et al., 2024)

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