optic neuritis glp 1 NAION and GLP1s: Rare Cause of Blindness Linked to Medication | Michael Weintraub, MD posted on the topic Sight Unseen: Glucagon-Like Peptide-1 (GLP-1)

Decreased FAO also appears to contribute to disease exacerbation as increased c-MYC upregulates miR-17 in mouse cystic kidneys inhibiting PPAR and leading to FAO inhibition to support proliferation of ADPKD cells

With a mean follow-up of 2.6 years, the study demonstrated a 34% reduction in the relative risk (RR) of a composite renal outcome, including dialysis requirement, a decline in glomerular filtration rate (GFR) 7% were initiated on the complementary drug to complete the GLP-1 RA + SGLT-2i combination therapy

Imagine if we spent as much energy predicting risk as we do managing complications

Prioritizing protein content, fat, calorie, and sugar reduction while boosting the nutritional value of products will be essential