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Like GPX4, phospholipase A2 (PLA 2 ) family members have been implicated in modulating ferroptosis sensitivity

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When we wrap glutathione in these phospholipids, we create a protective shield

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263,264 Apart from intracellular antioxidants like glutathione (GSH), heme oxygenase-1 (HO-1), superoxide dismutase-1, and nicotinamide adenine dinucleotide phosphate (NAPDH), MTs also serve as a redox buffer by interacting with and scavenging reactive species

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