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Lysosomal inhibitor Baf-A1 and autophagy inhibitor 3-MA also protected against cell death induced by GSH depletion, highlighting the role of autophagy in ferroptosis

31 Since the 2021 review, one more RCT has been published that compared oral B12 alone, 25 g per day (form not reported), or with folate (800 g per day) versus no supplements for 6 months in patients with mild cognitive impairment

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Both the 2.4 mg/week and 4.5 mg/week cagrilintide + semaglutide groups demonstrated an additional -7.4% weight loss compared to the semaglutide-only group [10]