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If a med goes through your liver, its taxing it, so you need a liver-loving nutrient like NAC or glutathione. Cohen lists the following classes of medications that are known to deplete Glutathione2: Acid blockers Analgesics Antacids Antibiotics Antivirals Tricyclic antidepressants Excess Body Fat Excess body fat triggers overproduction of several damaging proteins known to cause oxidative stress

There is in fact good evidence that the number of particles matters, such that having a large number of small particles is worse than having a small number of large particles

How GLP-1s cause weight loss There are three GLP-1 agonists approved in the last few years for the treatment of obesity: tirzepatide (Zepbound), semaglutide (Wegovy), and liraglutide (Saxenda)

The third, and most expensive, is compounded tirzepatide in injectable form