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L68Q-hCC is highly amyloidogenic, and subjects carrying the corresponding mutation suffer from severe cerebral amyloidosis, leading to brain hemorrhage and death in early adult life 26

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[DOI] [PubMed] [Google Scholar] [220].Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G, Zhu L, Du X, Petrov A, Lassman ME, Jiang G, Liu F, Miller C, Tota LM, Zhou G, Zhang X, Sountis MM, Santoprete A, Capito E, Chicchi GG, Thornberry N, Bianchi E, Pessi A, Marsh DJ, SinhaRoy R, Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice, Diabetes, 58 (2009) 22582266