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In a retrospective cohort study including 7,044 patients with T2D, obesity (BMI 27 kg/m 2 ) and HFpEF, combination therapy with an SGLT2i and GLP-1 RA showed a lower risk of HF exacerbation, all-cause emergency department visits and new-onset kidney injury compared with patients only receiving SGLT2i

Common regimens include 50 mg/kg intraperitoneally twice daily for 1228 days in C57BL/6J or ob/ob mice, with indirect calorimetry and body-composition endpoints

Everyone living in the household will have their income and resources considered when applying

Recently, glucagon-like peptide 1 receptor agonists (GLP- 1RAs) have emerged as safe and effective treatments for diabetes and obesity