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First, under normal conditions, elevated HO1 expression attenuates oxidative stress to exert cytoprotective effects, and second, sustained HO1 upregulation releases ferrous iron to exacerbate oxidative stress, which leads to ROS accumulation through the Fenton reaction

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The Polar H10 was specifically chosen for its ability to provide consistent real-time heart rate data, a key indicator of exercise intensity and endurance capacity