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7.6 Implications for evidence synthesis Taken together, these five sources of heterogeneity imply that the pooled effect estimates from existing meta-analyses (97, 119, 125, 126) should be viewed as broad directional signals rather than precise quantitative estimates applicable to specific clinical populations

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Abstract Background The aim of the study was to determine the potential of a low-fat diet (LFD) to protect against oxidative and inflammatory damage in the course of asthma and obesity when combined with antioxidants (alpha-lipoic acidALA, apocyninAPO) or a probiotic (P) ( Lactobacillus casei )