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Safe GLP-1 Use: Monitoring and Prevention Strategies Starting GLP-1 therapy at the lowest effective dose allows your digestive system to adapt gradually while minimizing gastrointestinal disruption

Although achieving surrogate histopathological endpoints is considered by regulatory agencies to likely translate to improved prognosis, robust evidence is needed to understand if GLP1 agonists reduce the risk of long-term clinical outcomes, such as liver decompensation or HCC, Axel Wester, MD, PhD, assistant professor of medicine at Karolinska Institute, and colleagues wrote

2,3 GLP-1 and Weight Loss GLP-1 is a hormone naturally produced in the central nervous system, intestine and pancreas

Statistical significance thresholds were maintained as previously described, where p-value below 0.05 was considered significant enrichment