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BIOCHEMICAL FUNCTIONS & CLINICAL RELEVANCE OF GLUTATHIONE Antioxidant Defense & Redox Regulation GSH is the most abundant intracellular antioxidant, neutralizing reactive oxygen (ROS), reactive nitrogen (RNS), and reactive sulfur (RSS) species (5-6)

Its promoter region contains eight stress-responsive cis-acting elements linked to phytohormones and stress pathways, including abscisic acid, MeJA (methyl jasmonate), gibberellin and salicylic acid ( III stress and reduces levels of the lipid peroxidation marker MDA, highlighting its potential as a target for crop improvement ( Arabidopsis , mirroring the function of mammalian CHAC2 ( AtGGCT2;2 contains cis-elements responsive to auxin, MeJA and low temperature