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However, a short period (2 weeks) of severe food restriction in rats was responsible for endothelial dysfunction in mesenteric arteries and for ischemia-reperfusion-induced arrhythmias and cardiac pathology (Almeida et al., )

Supplementary Table 10 (download XLSX GO enrichment analysis of differentially expressed genes in rat bulk RNA-seq across all treatments

Global Impact Orforgliprons success could revolutionize obesity management, especially in countries like India, where acceptance of injectable drugs remains limited

however, the risk does appear to be low, and further research is needed to support such direct findings