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While it has been touted as a natural remedy for weight loss because of its apparent effects on adipose tissue (the substance that stores fat), its effects have not been clearly defined as we read in the following National Institutes of Health study quote: Although its effects on immune cells are relatively well described, the mechanisms underlying bromelains actions on adipocytes remain incompletely understood

Its harder to study females because we have hormonal changes

Screening for varices in MAFLD cirrhosis There is insufficient data to support the utilization of any serological markers such as platelet count alone or the enhanced liver fibrosis panel to exclude CSPH and eliminate the need for endoscopic assessment in detecting varices that require treatment

McClean PL, Parthsarathy V, Faivre E, Holscher C: The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimers disease