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Epithalon is considered one most promising synthetic tetrapeptide compounds in current longevity research, largely due to its proposed mechanism of telomerase activation in aging cell populations

Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection

This process, known as paracrine signaling, allows exosomes to interact with cells in various ways - activating receptors on cell surfaces, merging with target cell membranes to release their cargo, or influencing the surrounding environment

Mechanisms: Its ability to support microvascular integrity, enhance fibroblast migration, and reduce oxidative stress facilitates recovery across muscle, tendon, ligament, nerve, gastrointestinal lining, and skin