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The immune system has different branches, primarily Th1 and Th2

When B12 levels are borderline, clinical suspicion remains high, or total B12 is unreliable (as in chronic liver disease), additional tests can provide clarity

For patients with pernicious anemia, severe malabsorption, or acute neurological symptoms, injections remain the appropriate clinical choice

On the other hand, spontaneous and often substantial functional improvements [53,54,55] after partial lesioning of the spinal cord are associated with the spontaneous sprouting of axons in the corticospinal tract [56,57,58] and the formation of neural circuits by spared spinal cord tissue [26]