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Therefore, while NAC reduces oxidative damage and lipid peroxidation, it does not influence liver fat deposition or liver function markers, highlighting its protective role against oxidative damage rather than modulating lipid metabolism

Journal of Biological Chemistry 277 , 4944649452, doi: 10.1074/jbc.M209372200 (2002)

In light of these data, we suggest therapies that target energy metabolism and ROS generation to improve kidney function recovery may need to also target the energy and redox derangements observed in the liver