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Abstract Ferroptosis is an iron-dependent programmed cell death process that involves lipid oxidation via the Fenton reaction to produce lipid peroxides, causing disruption of the lipid bilayer, which is essential for cellular survival

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The Pentose Phosphate Shunt functions as a source of NADPH and Ribose 5-phosphate The pentose phosphate shunt (also known as the hexose monophosphate shunt or the 6-phosphogluconate pathway) shares the intermediates glyceraldehyde-3-phosphate and fructose-6-phosphate with the glycolytic pathway

It is a major driver of falls, fractures, functional decline, and loss of independence in older adults