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The ustekinumab biosimilar market (Stelara reference, multiple approved biosimilars) is an example of a dermatology/gastroenterology biologic with strong biosimilar development, but it faces the competing next-generation branded challenge: AbbVies Skyrizi (risankizumab) has been actively marketed to physicians as a superior alternative to Stelara, complicating biosimilar market share projections

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