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A number of studies have looked at increasing glutathione levels in people with CF to improve lung function.[ref] Related article : Cystic fibrosis: How to check to see if you are a carrier of a CFTR mutation Alcohol: Long-term or heavy alcohol use depletes glutathione levels in the liver, causing alcoholic liver disease

Essentially, two groups can be distinguished: (i) molecules containing GSH or GSH-like moiety and (ii) molecules whose enzymatic activation occurs through a GSH-conjugate intermediate 109