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This allows it to pass through the intestinal wall and enter the bloodstream more effectively

Oxid Med Cell Longevity (2019) 2019:e7286737

In addition, transcription factors, such as activating transcription factor 4 (ATF4), nuclear factor erythroid 2-related factor 2 (Nrf2), and p53, can exert antioxidant effects by regulating the GSH/GPX4 pathway (4, 5)

IR influences GPX4 expression and cofactor availability IR can influence GPX4 activity by altering cystine transport, Glutathione Synthetase (GSS) synthesis, and GPX4 expression