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In a retrospective study of the postoperative course of 81 patients with adrenocorticotropic hormone independent Cushing syndrome, glucocorticoid withdrawal syndrome was most common when the 8 am serum cortisol level 24 hours after the last glucocorticoid dose was less than 5 g/dL, whereas no withdrawal symptoms were reported when it was higher than 10 g/dL

Unlike Aqualyx, which has been on the market in the UK since 2013 and has been studied in peer-reviewed work, Lemon Bottle has no comparable evidence base

10.1523/JNEUROSCI.5749-09.2010 80 RinamanL

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