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They are also nonselective drugs, which means that they not only act on melanocytes, increasing pigment production, but also in other cells involved in sexual function, energy homeostasis, immune function, and cardiovascular function

Being on any combination therapy early in the disease is associated with enduring advantages, sometimes termed "legacy effects," in which benefits lag behind for a while [39], [41]

The relative efficacy and relative cost of each comparator were then plotted on a costefficacy plane as the abscissa and ordinate, respectively (Figs

However, with age, pollution, stress, and UV exposure, the natural production of glutathione declines in the body